Long-term results of a randomised trial of involved field radiotherapy vs extended field radiotherapy in stage I and II Hodgkin lymphoma.

Journal article

Involved field (IF) radiation was compared with extended field (EF) radiation in Hodgkin lymphoma (HL) to ascertain whether reduced radiation fields would reduce the late sequelae of radiation without compromising disease control and survival. A total of 603 patients with stage I or II HL were entered into this trial; laparotomy was carried out in 380 (63%) patients. Stage I or IIA disease patients were randomised to receive IF or EF comprising a mantle or inverted Y fields alone. Stage I and...

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Authors: Hoskin, P; Smith, P; Maughan, T; Gilson, D; Vernon, C

• Publication status: Published
• Journal: Clinical oncology (Royal College of Radiologists (Great Britain))
• Volume: 17
• Issue: 1
• Pages: 47-53
• Publication date: 2005-02-01
• DOI: 10.1016/j.clon.2004.07.004
• EISSN: 1433-2981
• ISSN: 0936-6555
• Language: English
• Keywords: Middle Aged; Recurrence; Laparotomy; Adult; Neoplasm Staging; Treatment Outcome; Radiation Injuries; Male; Dose Fractionation; Adolescent; Aged; British National Lymphoma Investigation; Risk Factors; Female; Humans; Survival Analysis; Neoplasms, Radiation-Induced; Hodgkin Disease