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Bayesian coalescent inference of major human mtDNA haplogroup expansions in Africa

Abstract:

Summary: Past population size can be estimated from modern genetic diversity using coalescent theory. Estimates of ancestral human population dynamics in Africa can tell us about the timing and nature of our first steps towards colonizing the globe. Here we combine Bayesian coalescent inference with a dataset of 224 complete human mtDNA sequences to establish effective population size through time for each of the four major African mtDNA haplogroups (L0-L3). We find evidence of three distinct...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted Manuscript

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Publisher copy:
10.1098/rspb.2008.0785

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Institution:
University of Oxford
Oxford college:
Wolfson College
Department:
Social Sciences Division - Anthropology and Museum Ethnography,School of - Cognitive and Evolutionary Anthropology,Institute of
Role:
Author
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Institution:
University of Auckland, New Zealand
Department:
Department of Psychology
Role:
Author
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Institution:
University of Auckland, New Zealand
Department:
Bioinformatics Institute and Department of Computer Science
Role:
Author
Publisher:
Royal Society Publisher's website
Journal:
Proceedings of the Royal Society B: Biological Sciences Journal website
Volume:
276
Issue:
1655
Pages:
367-373
Publication date:
2009-01-05
DOI:
EISSN:
1471-2954
URN:
uuid:058af312-7f1a-4318-835d-b18094dc6646
Local pid:
ora:2799

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