Journal article
In vivo enhancer analysis of human conserved non-coding sequences.
- Abstract:
-
Identifying the sequences that direct the spatial and temporal expression of genes and defining their function in vivo remains a significant challenge in the annotation of vertebrate genomes. One major obstacle is the lack of experimentally validated training sets. In this study, we made use of extreme evolutionary sequence conservation as a filter to identify putative gene regulatory elements, and characterized the in vivo enhancer activity of a large group of non-coding elements in the huma...
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- Publication status:
- Published
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- Publisher copy:
- 10.1038/nature05295
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Authors
Bibliographic Details
- Journal:
- Nature
- Volume:
- 444
- Issue:
- 7118
- Pages:
- 499-502
- Publication date:
- 2006-11-01
- DOI:
- EISSN:
-
1476-4687
- ISSN:
-
0028-0836
- Source identifiers:
-
68001
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:68001
- UUID:
-
uuid:056410ae-6020-4c31-b207-ebd2a39a6703
- Local pid:
- pubs:68001
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2006
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