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Journal article

The natural history of multiple sclerosis: a geographically based study 10: relapses and long-term disability.

Abstract:

The relationship of relapses to long-term disability in multiple sclerosis is uncertain. Relapse reduction is a common therapeutic target but clinical trials have shown dissociation between relapse suppression and disability accumulation. We investigated relationships between relapses and disability progression for outcomes of requiring assistance to walk, being bedridden and dying from multiple sclerosis [Disability Status Scale 6, 8, 10] by analysing 28 000 patient-years of evolution in 806...

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Publication status:
Published

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Publisher copy:
10.1093/brain/awq118

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Journal:
Brain : a journal of neurology
Volume:
133
Issue:
Pt 7
Pages:
1914-1929
Publication date:
2010-07-01
DOI:
EISSN:
1460-2156
ISSN:
0006-8950
Source identifiers:
60452
Language:
English
Keywords:
UUID:
uuid:0559ead5-7990-4b36-b923-462f90f72f9f
Local pid:
pubs:60452
Deposit date:
2012-12-19

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