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Journal article

Differential and distributed effects of dopamine neuromodulations on resting-state network connectivity.

Abstract:

Dopaminergic medications, used to treat neurochemical pathology and resultant symptoms in neuropsychiatric disorders, are of mixed efficacy and regularly associated with behavioural side effects. The possibility that dopamine exerts both linear and nonlinear ('inverted U-shaped') effects on cognitive neurocircuitry may explain this outcome variability. However, it has proven to be difficult to characterise neural manifestations of psychopharmacological effects in humans. We hypothesised that ...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
Beckmann, CF More by this author
van Gerven, JM More by this author
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Journal:
NeuroImage
Volume:
78
Pages:
59-67
Publication date:
2013-09-05
DOI:
EISSN:
1095-9572
ISSN:
1053-8119
URN:
uuid:0557d379-22f3-46be-8ce4-2646b6ca67f3
Source identifiers:
396028
Local pid:
pubs:396028

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