Journal article
A unique protein phosphatase with kelch-like domains (PPKL) in Plasmodium modulates ookinete differentiation, motility and invasion.
- Abstract:
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Protein phosphorylation and dephosphorylation (catalysed by kinases and phosphatases, respectively) are post-translational modifications that play key roles in many eukaryotic signalling pathways, and are often deregulated in a number of pathological conditions in humans. In the malaria parasite Plasmodium, functional insights into its kinome have only recently been achieved, with over half being essential for blood stage development and another 14 kinases being essential for sexual developme...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 2.4MB)
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- Publisher copy:
- 10.1371/journal.ppat.1002948
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Authors
Funding
Bibliographic Details
- Publisher:
- Public Library of Science Publisher's website
- Journal:
- PLoS pathogens Journal website
- Volume:
- 8
- Issue:
- 9
- Pages:
- e1002948
- Publication date:
- 2012-09-01
- DOI:
- EISSN:
-
1553-7374
- ISSN:
-
1553-7366
- Source identifiers:
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353931
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:353931
- UUID:
-
uuid:053fdb56-2319-4b74-8782-a14a185f4899
- Local pid:
- pubs:353931
- Deposit date:
- 2013-11-16
Terms of use
- Copyright holder:
- Guttery et al
- Copyright date:
- 2012
- Notes:
- Copyright 2012 Guttery et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- Licence:
- CC Attribution (CC BY)
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