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Journal article

A unique protein phosphatase with kelch-like domains (PPKL) in Plasmodium modulates ookinete differentiation, motility and invasion.

Abstract:

Protein phosphorylation and dephosphorylation (catalysed by kinases and phosphatases, respectively) are post-translational modifications that play key roles in many eukaryotic signalling pathways, and are often deregulated in a number of pathological conditions in humans. In the malaria parasite Plasmodium, functional insights into its kinome have only recently been achieved, with over half being essential for blood stage development and another 14 kinases being essential for sexual developme...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1371/journal.ppat.1002948

Authors


Guttery, DS More by this author
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Institution:
University of Oxford
Szöőr, B More by this author
Wickstead, B More by this author
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Funding agency for:
Ferguson, DJ
Publisher:
Public Library of Science Publisher's website
Journal:
PLoS pathogens Journal website
Volume:
8
Issue:
9
Pages:
e1002948
Publication date:
2012-09-05
DOI:
EISSN:
1553-7374
ISSN:
1553-7366
URN:
uuid:053fdb56-2319-4b74-8782-a14a185f4899
Source identifiers:
353931
Local pid:
pubs:353931

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