Automated subtyping of HIV-1 genetic sequences for clinical and surveillance purposes: performance evaluation of the new REGA version 3 and seven other tools.

Pineda-Peña, A; Faria, N; Imbrechts, S; Libin, P; Abecasis, AB; Deforche, K; Gómez-López, A; Camacho, R; de Oliveira, T; Vandamme, A

Journal article

Automated subtyping of HIV-1 genetic sequences for clinical and surveillance purposes: performance evaluation of the new REGA version 3 and seven other tools.

Abstract:: BACKGROUND: To investigate differences in pathogenesis, diagnosis and resistance pathways between HIV-1 subtypes, an accurate subtyping tool for large datasets is needed. We aimed to evaluate the performance of automated subtyping tools to classify the different subtypes and circulating recombinant forms using pol, the most sequenced region in clinical practice. We also present the upgraded version 3 of the Rega HIV subtyping tool (REGAv3). METHODOLOGY: HIV-1 pol sequences (PR+RT) for 4674 pa...
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Publication status:: Published

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APA Style

Pineda-Peña, A., Faria, N., Imbrechts, S., Libin, P., Abecasis, A. B., Deforche, K., Gómez-López, A., Camacho, R., de Oliveira, T., & Vandamme, A. (2013). Automated subtyping of HIV-1 genetic sequences for clinical and surveillance purposes: performance evaluation of the new REGA version 3 and seven other tools. Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases, 19, 337–348.

MLA Style

Pineda-Peña, A., et al. “Automated Subtyping of HIV-1 Genetic Sequences for Clinical and Surveillance Purposes: Performance Evaluation of the New REGA Version 3 and Seven Other Tools.” Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases, vol. 19, 2013, pp. 337–48.

Chicago Style

Pineda-Peña, A, N Faria, S Imbrechts, P Libin, AB Abecasis, K Deforche, A Gómez-López, R Camacho, T de Oliveira, and A Vandamme. 2013. “Automated Subtyping of HIV-1 Genetic Sequences for Clinical and Surveillance Purposes: Performance Evaluation of the New REGA Version 3 and Seven Other Tools.” Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases 19: 337–48.
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