Journal article
TrkB modulates fear learning and amygdalar synaptic plasticity by specific docking sites.
- Abstract:
-
Understanding the modulation of the neural circuitry of fear is clearly one of the most important aims in neurobiology. Protein phosphorylation in response to external stimuli is considered a major mechanism underlying dynamic changes in neural circuitry. TrkB (Ntrk2) neurotrophin receptor tyrosine kinase potently modulates synaptic plasticity and activates signal transduction pathways mainly through two phosphorylation sites [Y515/Shc site; Y816/PLCgamma (phospholipase Cgamma) site]. To iden...
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- Publisher copy:
- 10.1523/jneurosci.1707-09.2009
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Bibliographic Details
- Journal:
- The Journal of neuroscience : the official journal of the Society for Neuroscience
- Volume:
- 29
- Issue:
- 32
- Pages:
- 10131-10143
- Publication date:
- 2009-08-05
- DOI:
- EISSN:
-
1529-2401
- ISSN:
-
0270-6474
- URN:
-
uuid:052e07c8-fc73-4385-8fc0-f464daacef9d
- Source identifiers:
-
329249
- Local pid:
- pubs:329249
Item Description
- Language:
- English
- Keywords:
Terms of use
- Copyright date:
- 2009
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