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Synthesis and characterization of polystyrene embolization particles doped with tantalum oxide nanoparticles for X-ray contrast.

Abstract:

Radiopaque and fluorescent embolic particles have been synthesized and characterised to match the size of vasculature found in tumours to ensure effective occlusion of the vessels. A literature search showed that the majority of vessels surrounding a tumour were less than 50 µm and therefore polydispersed polystyrene particles with a peak size of 50 µm have been synthesised. The embolic particles contain 5-8 nm amorphous tantalum oxide nanoparticles which provide X-ray contrast. Embolic parti...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1007/s10856-015-5549-5

Authors


More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Engineering Science
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Oncology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Oncology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Oncology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Women's and Reproductive Health
Role:
Author
More from this funder
Name:
Research Councils UK
Funding agency for:
Morrison, R
Grant:
EP/G036861/1
More from this funder
Name:
Williams Fund
Funding agency for:
Townley, H
More from this funder
Name:
Medical Research Council
Funding agency for:
Thompson, J
Bird, L
Hill, M
Publisher:
Springer US
Journal:
Journal of materials science. Materials in medicine More from this journal
Volume:
26
Issue:
8
Pages:
5549
Publication date:
2015-01-01
DOI:
EISSN:
1573-4838
ISSN:
0957-4530
Language:
English
Pubs id:
pubs:535505
UUID:
uuid:052874c1-51cd-4de1-8d25-45193557acc8
Local pid:
pubs:535505
Source identifiers:
535505
Deposit date:
2015-10-09

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