Journal article
Depot-specific prostaglandin synthesis in human adipose tissue: a novel possible mechanism of adipogenesis.
- Abstract:
-
Despite the magnitude of the obesity epidemic, the mechanisms that contribute to increases in fat mass and to differences in fat depots are still poorly understood. Prostanoids have been proposed as potent adipogenic hormones, e.g. metabolites of prostaglandin J2 (PGJ2) bind and activate PPARgamma. We hypothesize that an altered expression of enzymes in PGJ2 synthesis may represent a novel pathogenic mechanism in human obesity. We characterized adipose depot-specific expression of enzymes in ...
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- Publication status:
- Published
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- Publisher copy:
- 10.1016/j.gene.2006.05.026
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Authors
Bibliographic Details
- Journal:
- Gene
- Volume:
- 380
- Issue:
- 2
- Pages:
- 137-143
- Publication date:
- 2006-10-05
- DOI:
- EISSN:
-
1879-0038
- ISSN:
-
0378-1119
- URN:
-
uuid:05232e66-35f2-4968-830f-e26ad3bd05e5
- Source identifiers:
-
482101
- Local pid:
- pubs:482101
Item Description
- Language:
- English
- Keywords:
Terms of use
- Copyright date:
- 2006
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