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Endogenous erythropoietin as part of the cytokine network in the pathogenesis of experimental autoimmune encephalomyelitis.

Abstract:

Erythropoietin (EPO) is of great interest as a therapy for many of the central nervous system (CNS) diseases and its administration is protective in experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis (MS). Endogenous EPO is induced by hypoxic/ischemic injury, but little is known about its expression in other CNS diseases. We report here that EPO expression in the spinal cord is induced in mouse models of chronic or relapsing-remitting EAE, and is prominentl...

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Publisher copy:
10.2119/2008-00086.mengozzi

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
Journal:
Molecular medicine (Cambridge, Mass.) More from this journal
Volume:
14
Issue:
11-12
Pages:
682-688
Publication date:
2008-01-01
DOI:
EISSN:
1528-3658
ISSN:
1076-1551
Language:
English
Keywords:
Pubs id:
pubs:470792
UUID:
uuid:050deb23-220b-4787-adfe-7cc5a447ab7f
Local pid:
pubs:470792
Source identifiers:
470792
Deposit date:
2014-07-08

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