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Journal article

Non-covalent single transcription factor encapsulation inside a DNA cage.

Abstract:
CAP-turing the moment: A cage made from DNA can be used to encapsulate a transcription factor (catabolite activator protein, CAP; see figure) without covalent attachment. CAP is shown to stably bind inside the DNA cage at a 1:1 ratio by bending one edge to accommodate the protein. Single-molecule fluorescence measurements confirm the orientation of CAP within the cage. Copyright © 2013 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim.
Publication status:
Published

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Publisher copy:
10.1002/anie.201207914

Authors

More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Physics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Role:
Author


Journal:
Angewandte Chemie (International ed. in English) More from this journal
Volume:
52
Issue:
8
Pages:
2284-2288
Publication date:
2013-02-01
DOI:
EISSN:
1521-3773
ISSN:
1433-7851


Language:
English
Keywords:
Pubs id:
pubs:374198
UUID:
uuid:0505430e-4a0e-48f6-b5e0-c2fafd6c0f89
Local pid:
pubs:374198
Source identifiers:
374198
Deposit date:
2013-11-16
ARK identifier:

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