Journal article
Macrophages and the hypoxic tumour microenvironment.
- Abstract:
-
One characteristic of solid tumour tissue is the presence of large numbers of tumour-associated macrophages. These migrate down gradients of chemo-attractive agents to accumulate within hypoxic and / or necrotic areas where they are generally related to poor clinical prognosis. In this review we will discuss the molecular mechanisms that underlie recruitment of macrophages into tumours and their pro-tumourigenic activities with respect to stimulation of angiogenesis, lymphangiogenesis, tumour...
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- Publication status:
- Published
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Bibliographic Details
- Journal:
- Frontiers in bioscience : a journal and virtual library
- Volume:
- 12
- Issue:
- 11
- Pages:
- 4298-4314
- Publication date:
- 2007-01-01
- DOI:
- EISSN:
-
1093-4715
- ISSN:
-
1093-9946
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:108460
- UUID:
-
uuid:04f1473d-f1aa-4b47-b921-3e5d94f62041
- Local pid:
- pubs:108460
- Source identifiers:
-
108460
- Deposit date:
- 2012-12-19
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- Copyright date:
- 2007
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