Journal article
Host gene expression signatures to identify infection type and organ dysfunction in children evaluated for sepsis: a multicentre cohort study
- Abstract:
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Background: Sepsis is defined as dysregulated host response to infection that leads to life-threatening organ dysfunction. Biomarkers characterising the dysregulated host response in sepsis are lacking. We aimed to develop host gene expression signatures to predict organ dysfunction in children with bacterial or viral infection.
Methods: This cohort study was done in emergency departments and intensive care units of four hospitals in Queensland, ...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Preview, Version of record, pdf, 414.9KB, Terms of use)
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- Publisher copy:
- 10.1016/s2352-4642(24)00017-8
Authors
Contributors
+ EUCLIDS Consortium
- Role:
- Contributor
+ RAPIDS Study Group
- Role:
- Contributor
+ Pollard, AJ
- Institution:
- University of Oxford
- Division:
- MSD
- Department:
- Paediatrics
- Sub department:
- Paediatrics
- Role:
- Contributor
- Publisher:
- Elsevier
- Journal:
- Lancet Child and Adolescent Health More from this journal
- Volume:
- 8
- Issue:
- 5
- Pages:
- 325-338
- Place of publication:
- England
- Publication date:
- 2024-03-18
- Acceptance date:
- 2024-01-15
- DOI:
- EISSN:
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2352-4650
- ISSN:
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2352-4642
- Pmid:
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38513681
- Language:
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English
- Keywords:
- Pubs id:
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1988192
- Local pid:
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pubs:1988192
- Deposit date:
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2024-04-11
- ARK identifier:
Terms of use
- Copyright holder:
- Elsevier
- Copyright date:
- 2024
- Rights statement:
- © 2024 The Authors. Published by Elsevier Ltd. User License: Creative Commons Attribution (CC BY 4.0)
- Licence:
- CC Attribution (CC BY)
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