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Journal article

Recent advances in antibody-inducing poxviral and adenoviral vectored vaccine delivery platforms for difficult disease targets.

Abstract:

Viral vectored vaccine delivery platforms have traditionally been used for the induction of cellular rather than humoral immunity. However, in recent years, recombinant adenoviral and poxviral vectored vaccines have been optimized to induce B-cell responses, resulting in the demonstration of high-titer antibody responses in a wide variety of animal species. These approaches have now been translated, confirming the induction of substantial levels of antigen-specific IgG in a series of Phase I ...

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Publication status:
Published

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Publisher copy:
10.1586/erv.13.11

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Jenner Institute
Role:
Author
Journal:
Expert review of vaccines
Volume:
12
Issue:
4
Pages:
365-378
Publication date:
2013-04-01
DOI:
EISSN:
1744-8395
ISSN:
1476-0584
Source identifiers:
394954
Language:
English
Keywords:
Pubs id:
pubs:394954
UUID:
uuid:04ab3a3e-16f0-46f8-9a71-dae6cf0c2a0c
Local pid:
pubs:394954
Deposit date:
2013-11-16

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