- Abstract:
-
OBJECTIVES: Dementia in Alzheimer's disease correlates closely with loss of neocortical synapses. Similar synaptic loss has been shown in patients whose Alzheimer's disease is also associated with neocortical and brain stem Lewy bodies. The aim was to determine if dementia in Lewy body disease was associated with diminished concentrations of midfrontal cortex synaptophysin. METHODS: An immunobinding assay was used to measure synaptophysin in postmortem samples of midfrontal cortex from 89 pat...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1136/jnnp.64.5.653
-
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- Journal:
- Journal of neurology, neurosurgery, and psychiatry
- Volume:
- 64
- Issue:
- 5
- Pages:
- 653-656
- Publication date:
- 1998-05-05
- DOI:
- EISSN:
-
1468-330X
- ISSN:
-
0022-3050
- URN:
-
uuid:049a3c05-e96d-4d7d-b16a-d82b4dac4fae
- Source identifiers:
-
36186
- Local pid:
- pubs:36186
- Language:
- English
- Keywords:
- Copyright date:
- 1998
Journal article
Frontal cortical synaptophysin in Lewy body diseases: relation to Alzheimer's disease and dementia.
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