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Nonlinear acoustic properties of ex vivo bovine liver and the effects of temperature and denaturation.

Abstract:

Thermal ablation by high intensity focused ultrasound (HIFU) has a great potential for the non-invasive treatment of solid tumours. Due to the high pressure amplitudes involved, nonlinear acoustic effects must be understood and the relevant medium property is the parameter of nonlinearity B/A. Here, B/A was measured in ex vivo bovine liver, over a heating/cooling cycle replicating temperatures reached during HIFU ablation, adapting a finite amplitude insertion technique, which also allowed fo...

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Publication status:
Published

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Authors


Jackson, EJ More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MPLS, Engineering Science
Cleveland, RO More by this author
Publisher:
Institute of Physics Publishing
Journal:
Physics in medicine and biology
Volume:
59
Issue:
12
Pages:
3223-3238
Publication date:
2014-06-05
DOI:
EISSN:
1361-6560
ISSN:
0031-9155
URN:
uuid:0485de6a-2f4c-4428-a541-0bbf81a979dd
Source identifiers:
466113
Local pid:
pubs:466113

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