- Abstract:
-
The influence of the position of the CG.C+ triplet and the contribution of protonation at the N3 of the Hoogsteen cytosine residue on the stability of various sequences of parallel triple helices having the general composition d[(A5G)-x-(T5C)-x-(T5C)] and d[(A4G2)-x-(T4C2)-x-(T4C2)], where x is the hexaethylene glycol linker, has been determined by NMR, ultraviolet melting and absorbance spectrophotometry. The apparent pK value, i.e. the pH at which the observable has changed by 50% of its ra...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1006/jmbi.1997.1520
-
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- Publisher:
- Academic Press
- Journal:
- Journal of molecular biology
- Volume:
- 275
- Issue:
- 5
- Pages:
- 811-822
- Publication date:
- 1998-02-05
- DOI:
- EISSN:
-
1089-8638
- ISSN:
-
0022-2836
- URN:
-
uuid:0483f963-9208-40cf-a024-ac01edb99187
- Source identifiers:
-
400270
- Local pid:
- pubs:400270
- Language:
- English
- Keywords:
- Copyright date:
- 1998
Journal article
The contribution of cytosine protonation to the stability of parallel DNA triple helices.
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