Journal article
Cranial irradiation for cerebral and nasopharyngeal tumours in children: evidence for the production of a hypothalamic defect in growth hormone release.
- Abstract:
-
A synthetic 29-amino acid analogue of human pancreatic GH-releasing hormone (GHRH(1-29)NH2) has recently been shown to stimulate the release of GH in normal subjects. We have studied the GH response to GHRH(1-29)NH2 in nine children irradiated for brain and nasopharyngeal tumours, who were not growing and were deficient in GH as assessed by insulin-induced hypoglycaemia. Serum GH rose in response to GHRH(1-29)NH2 in all the children, and in five the peak serum GH response was greater than 20 ...
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- Publication status:
- Published
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- Publisher copy:
- 10.1677/joe.0.1080025
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Bibliographic Details
- Journal:
- The Journal of endocrinology
- Volume:
- 108
- Issue:
- 1
- Pages:
- 25-29
- Publication date:
- 1986-01-05
- DOI:
- EISSN:
-
1479-6805
- ISSN:
-
0022-0795
- URN:
-
uuid:047a9284-6966-4beb-aecb-37a477405353
- Source identifiers:
-
138510
- Local pid:
- pubs:138510
Item Description
Terms of use
- Copyright date:
- 1986
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