Journal article
A rapid flow cytometric assay to detect CD4+ and CD8+ T-helper (Th) 0, Th1 and Th2 cells in whole blood and its application to study cytokine levels in atopic dermatitis before and after cyclosporin therapy.
- Abstract:
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BACKGROUND: The immune response in atopic dermatitis (AD) is thought to be driven by T-helper (Th) 2 cytokines. Using flow cytometry, higher frequencies of peripheral blood CD4+ and CD8+ T cells producing interleukin (IL)-4 and correspondingly lower frequencies of CD4+ T cells producing interferon (IFN)-gamma have been found in patients with AD compared with healthy controls. It would be of interest to know whether other Th1 and Th2 cytokines such as IL-5, IL-13 and tumour necrosis factor (TN...
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- Publisher copy:
- 10.1046/j.1365-2133.2001.03948.x
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Authors
Bibliographic Details
- Journal:
- British journal of dermatology
- Volume:
- 144
- Issue:
- 1
- Pages:
- 24-33
- Publication date:
- 2001-01-01
- DOI:
- EISSN:
-
1365-2133
- ISSN:
-
0007-0963
- Source identifiers:
-
94166
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:94166
- UUID:
-
uuid:0464225f-d1e0-4fa3-992d-b75b5060cb9e
- Local pid:
- pubs:94166
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2001
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