Imaging CNS modulation of pain in humans.

Journal article

Pain is a highly complex and subjective experience that is not linearly related to the nociceptive input. What is clear from anecdotal reports over the centuries and more recently from animal and human experimentation is that nociceptive information processing and consequent pain perception is subject to significant pro- and anti-nociceptive modulations. These modulations can be initiated reflexively or by contextual manipulations of the pain experience including cognitive and emotional facto...

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Authors: Bingel, U; Tracey, I

• Publication status: Published
• Journal: Physiology (Bethesda, Md.)
• Volume: 23
• Issue: 6
• Pages: 371-380
• Publication date: 2008-12-01
• DOI: 10.1152/physiol.00024.2008
• EISSN: 1548-9221
• ISSN: 1548-9213
• Language: English
• Keywords: Nociceptors; Chronic Disease; Brain Chemistry; Humans; Neural Pathways; Pain; Central Nervous System; Animals