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Is the predictive power of previous fractures for new spine and non-spine fractures associated with biochemical evidence of altered bone remodelling? The EPOS study. European Prospective Osteoporosis Study.

Abstract:

BACKGROUND: In the European Prospective Osteoporosis Study (EPOS), a past spine fracture increased risk of an incident fracture 3.6 - 12-fold even after adjusting for BMD. We examined the possibility that biochemical marker levels were associated with this unexplained BMD-independent element of fracture risk. METHODS: Each of 182 cases in EPOS of spine or non-spine fracture that occurred in 3.8 years of follow-up was matched by age, sex and study centre with two randomly assigned never-fract...

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Publication status:
Published

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Journal:
Clinica chimica acta; international journal of clinical chemistry
Volume:
322
Issue:
1-2
Pages:
121-132
Publication date:
2002-08-05
DOI:
EISSN:
1873-3492
ISSN:
0009-8981
URN:
uuid:044aa6d2-258b-4f21-af3d-3a3eb4f6d649
Source identifiers:
473784
Local pid:
pubs:473784

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