Journal article
A mathematical model of the slow force response to stretch in rat ventricular myocytes
- Abstract:
-
We developed a model of the rat ventricular myocyte at room temperature to predict the relative effects of different mechanisms on the cause of the slow increase in force in response to a step change in muscle length. We performed simulations in the presence of stretch-dependent increases in flux through the Na(+)-H(+) exchanger (NHE) and Cl(-)-HCO(3)(-) exchanger (AE), stretch-activated channels (SAC), and the stretch-dependent nitric oxide (NO) induced increased open probability of the ryan...
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Bibliographic Details
- Journal:
- Biophys J
- Volume:
- 92
- Issue:
- 11
- Pages:
- 4030-44
- Publication date:
- 2007-01-01
Item Description
- UUID:
-
uuid:04435aa5-cc63-4f76-9c50-3b2253652667
- Local pid:
- cs:1525
- Deposit date:
- 2015-03-31
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- Copyright date:
- 2007
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