Journal article
Active viral genes in transformed cells lie close to the nuclear cage.
- Abstract:
-
Nuclear DNA is looped by attachment to a matrix or cage. Using nine different lines transformed by polyoma or avian sarcoma virus, we have mapped viral sequences integrated within these loops. In all lines that contain high concentrations of viral transcripts and express the transformed phenotype, the integrated viral genes lie close to the points of attachment to the cage. Integration of polyoma DNA induces outlying cellular sequences to become closely associated with the cage. The strength ...
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- Publication status:
- Published
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Bibliographic Details
- Journal:
- EMBO journal
- Volume:
- 1
- Issue:
- 4
- Pages:
- 447-452
- Publication date:
- 1982-01-01
- EISSN:
-
1460-2075
- ISSN:
-
0261-4189
- Source identifiers:
-
3677
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:3677
- UUID:
-
uuid:043d06d0-dc1c-47f5-8843-dfc2d45ae157
- Local pid:
- pubs:3677
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 1982
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