A whole-blood assay (WBA), which assesses the complete bactericidal activity of blood, was compared with the serum bactericidal assay (SBA), which measures antibody and complement mediated cell lysis. Twenty children infected with serogroup B strains and 25 infected with serogroup C strains were studied 8-12 weeks after disease, and 29 healthy children were used as controls. The infecting strain (convalescent children only) and two reference strains, MC58 (B:15:P1.7, 16) and NCTC 8554 (C:NT:P...Expand abstract
- Publication status:
- Publisher copy:
- Copyright date:
Assessment of immune response to meningococcal disease: comparison of a whole-blood assay and the serum bactericidal assay.
Views and Downloads
If you are the owner of this record, you can report an update to it here: Report update to this record