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Assessment of immune response to meningococcal disease: comparison of a whole-blood assay and the serum bactericidal assay.

Abstract:

A whole-blood assay (WBA), which assesses the complete bactericidal activity of blood, was compared with the serum bactericidal assay (SBA), which measures antibody and complement mediated cell lysis. Twenty children infected with serogroup B strains and 25 infected with serogroup C strains were studied 8-12 weeks after disease, and 29 healthy children were used as controls. The infecting strain (convalescent children only) and two reference strains, MC58 (B:15:P1.7, 16) and NCTC 8554 (C:NT:P...

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Publication status:
Published

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Publisher copy:
10.1006/mpat.1999.0296

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Journal:
Microbial pathogenesis
Volume:
27
Issue:
4
Pages:
207-214
Publication date:
1999-10-05
DOI:
EISSN:
1096-1208
ISSN:
0882-4010
URN:
uuid:0427f950-13fd-42b6-ba8f-dfec76e6234a
Source identifiers:
122275
Local pid:
pubs:122275

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