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Journal article

Genetic pleiotropy between age-related macular degeneration and 16 complex diseases and traits

Abstract:

BACKGROUND:Age-related macular degeneration (AMD) is a common condition of vision loss with disease development strongly influenced by environmental and genetic factors. Recently, 34 loci were associated with AMD at genome-wide significance. So far, little is known about a genetic overlap between AMD and other complex diseases or disease-relevant traits. METHODS:For each of 60 complex diseases/traits with publicly available genome-wide significant association data, the lead genetic variant pe...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1186/s13073-017-0418-0

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Grant:
U10 EY006594
R01 EY022310
P30 EY001583
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Grant:
HHSN268201200008C
HHSN268201200008I
Publisher:
BioMed Central Publisher's website
Journal:
Genome Medicine Journal website
Volume:
9
Issue:
1
Article number:
29
Publication date:
2017-03-27
Acceptance date:
2017-03-02
DOI:
EISSN:
1756-994X
Pmid:
28347358
Language:
English
Keywords:
Pubs id:
pubs:915230
UUID:
uuid:041e0115-ad28-4848-9568-1142d9817c46
Local pid:
pubs:915230
Source identifiers:
915230
Deposit date:
2019-04-05

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