Long-term lithium therapy for bipolar disorder: systematic review and meta-analysis of randomized controlled trials.

Journal article

OBJECTIVE: The authors sought to determine the efficacy and acceptability of lithium for relapse prevention in bipolar disorder. METHOD: A systematic review and meta-analysis of randomized controlled trials comparing lithium with placebo in the long-term treatment of bipolar disorders was conducted. Data were obtained from searching the registers of the Cochrane Collaboration; reviewing reference lists, journals, and conference abstracts; and contacting authors, experts, and pharmaceutical c...

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Authors: Geddes, J; Burgess, S; Hawton, K; Jamison, K; Goodwin, G

• Publication status: Published
• Journal: American journal of psychiatry
• Volume: 161
• Issue: 2
• Pages: 217-222
• Publication date: 2004-02-01
• DOI: 10.1176/appi.ajp.161.2.217
• EISSN: 1535-7228
• ISSN: 0002-953X
• Language: English
• Keywords: Antimanic Agents; Time; Lithium Carbonate; Randomized Controlled Trials as Topic; Bipolar Disorder; Recurrence; Humans