Course and outcome of acute limbic encephalitis with negative voltage-gated potassium channel antibodies.

Journal article

BACKGROUND: Limbic encephalitis is a potentially treatable immunological condition. The presence of voltage-gated potassium channel antibodies (VGKC-Ab) in the cerebrospinal fluid (CSF) and serum of patients with the condition is a marker of the disease associated with a non-paraneoplastic form and good response to treatment. Recent work has highlighted absent serum VGKC-Ab and distinct immunology in patients with the paraneoplastic form of limbic encephalitis. METHODS: The cases of four pat...

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Authors: Samarasekera, SR; Vincent, A; Welch, J; Jackson, M; Nichols, P

• Publication status: Published
• Journal: Journal of neurology, neurosurgery, and psychiatry
• Volume: 78
• Issue: 4
• Pages: 391-394
• Publication date: 2007-04-01
• DOI: 10.1136/jnnp.2006.093096
• EISSN: 1468-330X
• ISSN: 0022-3050
• Language: English
• Keywords: Acute Disease; Seizures; Limbic Encephalitis; Potassium Channels, Voltage-Gated; Humans; Antibodies; Paraneoplastic Syndromes; Treatment Outcome; Predictive Value of Tests; Cognition Disorders; Female; Male; Magnetic Resonance Imaging; Adult