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Journal article

Prediction of favourable responses to long term vasodilator treatment of pulmonary hypertension by short term administration of epoprostenol (prostacyclin) or nifedipine.

Abstract:

Eighteen patients with moderate to severe pulmonary hypertension were studied, nine with intracardiac shunts and nine without. The effects of an incremental infusion of epoprostenol (prostacyclin) (0.5-8 ng/kg per minute) or sublingual nifedipine (20-30 mg) were compared with the response to three months' treatment with oral nifedipine. Both epoprostenol and sublingual nifedipine caused a fall in pulmonary vascular resistance and pressure and a rise in cardiac output. Patients with intracardi...

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Publication status:
Published

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Publisher copy:
10.1136/hrt.59.6.696

Authors


Rozkovec, A More by this author
Stradling, JR More by this author
Shepherd, G More by this author
MacDermot, J More by this author
Oakley, CM More by this author
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Publisher:
BMJ Publishing Group
Journal:
British heart journal
Volume:
59
Issue:
6
Pages:
696-705
Publication date:
1988-06-05
DOI:
ISSN:
0007-0769
URN:
uuid:03fe10ad-e0fc-422a-9168-b7fb6d16081d
Source identifiers:
71474
Local pid:
pubs:71474

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