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Genetic risk, incident gastric cancer, and healthy lifestyle: a meta-analysis of genome-wide association studies and prospective cohort study

Abstract:

Background
Genetic variants and lifestyle factors have been associated with gastric cancer risk, but the extent to which an increased genetic risk can be offset by a healthy lifestyle remains unknown. We aimed to establish a genetic risk model for gastric cancer and assess the benefits of adhering to a healthy lifestyle in individuals with a high genetic risk.
Methods
In this meta-analysis and prospective cohort study, we first did a fixed-... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/S1470-2045(20)30460-5

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Sub department:
Clinical Trial Service Unit
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Sub department:
Clinical Trial Service Unit
Role:
Author


Publisher:
Elsevier
Journal:
The Lancet Oncology More from this journal
Volume:
21
Issue:
10
Pages:
1378-1386
Publication date:
2020-10-01
Acceptance date:
2020-07-15
DOI:
EISSN:
1474-5488
ISSN:
1470-2045


Language:
English
Keywords:
Pubs id:
1137490
Local pid:
pubs:1137490
Deposit date:
2020-10-13

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