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Analysis of the peripheral T-cell repertoire in kidney transplant patients.

Abstract:

The long-term stability of renal grafts depends on the absence of chronic rejection. As T cells play a key role in rejection processes, analyzing the T-cell repertoire may be useful for understanding graft function outcomes. We have therefore investigated the power of a new statistical tool, used to analyze the peripheral blood TCR repertoire, for determining immunological differences in a group of 229 stable renal transplant patients undergoing immunosuppression. Despite selecting the patien...

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Publication status:
Published

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Publisher copy:
10.1002/eji.201040301

Authors


Degauque, N More by this author
Guillet, M More by this author
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Journal:
European journal of immunology
Volume:
40
Issue:
11
Pages:
3280-3290
Publication date:
2010-11-05
DOI:
EISSN:
1521-4141
ISSN:
0014-2980
URN:
uuid:03fc738c-74e1-4ada-991b-e51b81430ab6
Source identifiers:
136052
Local pid:
pubs:136052

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