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A synthesis of dioctanoyl phosphatidylinositol

Abstract:
A synthesis of the naturally occurring enantiomer of phosphatidylinositol is reported. A resolution strategy, using camphor as a chiral auxiliary is employed to obtain the desired, enantiomerically pure, inositol derivative. Dioctanoyl lipid chains are appended to the molecule, which are shorter than the naturally occurring lipid chains, providing the molecule with enhanced water solubility. © 2009 Elsevier Ltd. All rights reserved.
Publication status:
Published

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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Role:
Author
Journal:
TETRAHEDRON-ASYMMETRY
Volume:
20
Issue:
24
Pages:
2809-2813
Publication date:
2009-12-22
DOI:
EISSN:
1362-511X
ISSN:
0957-4166
Language:
English
Pubs id:
pubs:50325
UUID:
uuid:03f6315a-16d4-4a1e-9d2b-422eb5648ee0
Local pid:
pubs:50325
Source identifiers:
50325
Deposit date:
2012-12-19

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