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Systematic review and critical methodological appraisal of community-based falls prevention economic models

Abstract:
Background Three pathways exist for community-based falls prevention: reactive (R), after a fall requiring medical attention; proactive (P), after professional referral of high-risk individuals; and self-referred (SR), voluntary intervention enrolment. The UK guidelines recommend scale-up of all three [‘recommended care’ (RC)], but scale-up of none [‘usual care’ (UC)], one (R, P, SR) or two (R+P, R+SR, P+SR) are potential options. This study aims to compare the options in terms of efficiency and equity. Methods Cost-utility analysis from the societal perspective over a 40-year horizon identified the optimal strategy based on efficiency alone. Probabilistic sensitivity analysis accounted for parameter uncertainty. Efficiency and equity were jointly evaluated by distributional cost-effectiveness analysis. Alternative scenarios assessed changes in frailty, cognitive impairment, intervention demand and GP access. Results Public sector cost-effectiveness threshold would need to exceed £30 000 per quality-adjusted life year (QALY) gained for RC to have the highest probability of being cost-effective. R and R+SR were cost-effective, with costs per QALY gained of £2365 (R versus UC) and £5516 (R+SR versus R). RC was cost-ineffective, incurring £34 258 per QALY gained versus R+SR. Other strategies were dominated. However, if decision-makers had the same relative health inequality aversion level as the English general public, RC was optimal in terms of efficiency and equity at threshold of £30 000 per QALY gained. Scenarios of worse geriatric health favoured RC. Conclusions Both efficiency and relative health inequality need to be considered for the UK guideline-recommended falls prevention to be optimal versus other permutations of community-based strategies
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1186/s12962-022-00367-y
Publication website:
https://eprints.whiterose.ac.uk/id/eprint/230019/1/afaf212.pdf

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Institution:
University of Oxford
Role:
Author
ORCID:
0000-0002-2860-7280
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Role:
Author
ORCID:
0000-0001-8467-0471
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Role:
Author
ORCID:
0000-0002-2776-4014
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Role:
Author
ORCID:
0000-0002-0754-7223


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Funder identifier:
10.13039/100004440
Grant:
108903/B/15/Z


Publisher:
BioMed Central
Journal:
Cost Effectiveness and Resource Allocation More from this journal
Volume:
20
Issue:
1
Pages:
33-33
Article number:
33
Publication date:
2022-07-16
DOI:
EISSN:
1478-7547
ISSN:
1478-7547


Language:
English
Keywords:
Pubs id:
1268817
Local pid:
pubs:1268817
Source identifiers:
W4285587373
Deposit date:
2026-04-27
ARK identifier:
This ORA record was generated from metadata provided by an external service. It has not been edited by the ORA Team.

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