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Feedback Control Architecture and the Bacterial Chemotaxis Network

Abstract:
This paper investigates the chemotaxis behavior of the bacterium R. sphaeroides. We review the results of a recent study comparing different possible mathematical models of this bacterium's chemotaxis decision mechanisms. It was found that only one of the aforesaid models could explain the experimental chemotactic response data. From a control theoretic perspective, we show that, compared to the other models posed, this model exhibits better and more robust chemotactic performance. This decision mechanism parallels a feedback architecture that has been used extensively to improve performance in engineered systems. We suggest that this mechanism may play a role in maintaining the chemotactic performance of this and potentially other bacteria.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1371/journal.pcbi.1001130

Authors



Publisher:
Public Library of Science
Journal:
PLoS Computational Biology More from this journal
Volume:
7
Pages:
3014-3019
Publication date:
2011-05-05
Acceptance date:
2011-04-01
DOI:
ISSN:
0191-2216


Language:
English
Keywords:
Pubs id:
pubs:318850
UUID:
uuid:03e18fda-c590-4a44-b450-f0db9526d0fe
Local pid:
pubs:318850
Source identifiers:
318850
Deposit date:
2012-12-19

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