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MAP(K)ing the path to stem cell quiescence and the elusive enteroendocrine cell

Abstract:
The existence and interaction of proliferating and quiescent intestinal stem cells have been debated since their discovery in the 1970s. In this issue of Cell Stem Cell, using murine intestinal organoids, Basak et al. (2017) induce stem cell quiescence by selective inhibition of EGF/MAPK signaling and define culture conditions that direct differentiation to the enteroendocrine lineage.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.stem.2017.01.005

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Institution:
University of Oxford
Oxford college:
Magdalen College
Role:
Author
Publisher:
Elsevier Publisher's website
Journal:
Cell Stem Cell Journal website
Volume:
20
Issue:
2
Pages:
153-154
Publication date:
2017-02-02
Acceptance date:
2017-01-16
DOI:
EISSN:
1875-9777
ISSN:
1934-5909
Source identifiers:
680521
Keywords:
Pubs id:
pubs:680521
UUID:
uuid:03d93c27-36a2-4d48-b40a-eaaa192d54da
Local pid:
pubs:680521
Deposit date:
2017-02-21

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