- Abstract:
- The existence and interaction of proliferating and quiescent intestinal stem cells have been debated since their discovery in the 1970s. In this issue of Cell Stem Cell, using murine intestinal organoids, Basak et al. (2017) induce stem cell quiescence by selective inhibition of EGF/MAPK signaling and define culture conditions that direct differentiation to the enteroendocrine lineage.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Accepted manuscript
- Files:
-
-
(pdf, 127.7KB)
-
- Publisher copy:
- 10.1016/j.stem.2017.01.005
-
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- Publisher:
- Elsevier Publisher's website
- Journal:
- Cell Stem Cell Journal website
- Volume:
- 20
- Issue:
- 2
- Pages:
- 153-154
- Publication date:
- 2017-02-02
- Acceptance date:
- 2017-01-16
- DOI:
- EISSN:
-
1875-9777
- ISSN:
-
1934-5909
- Pubs id:
-
pubs:680521
- URN:
-
uri:03d93c27-36a2-4d48-b40a-eaaa192d54da
- UUID:
-
uuid:03d93c27-36a2-4d48-b40a-eaaa192d54da
- Local pid:
- pubs:680521
- Paper number:
- 2
- Keywords:
- Copyright holder:
- © 2017 Published by Elsevier Inc.
- Copyright date:
- 2017
- Notes:
- This is the author accepted manuscript following peer review version of the article. The final version is available online from Elsevier at: 10.1016/j.stem.2017.01.005
Journal article
MAP(K)ing the path to stem cell quiescence and the elusive enteroendocrine cell
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