Normal glutamate but elevated myo-inositol in anterior cingulate cortex in recovered depressed patients
Background: MRS studies of acutely depressed patients reveal decreased levels of total glutamate and glutamine (Glx) in frontal cortex which may reflect abnormalities of glutamate-glutamine cycling through astrocytes. Frontal Glx levels appear to be normalised after recovery from depression, but it is not known if this composite measure masks ongoing differences in glutamate or glutamine alone. Methods: Medication-free, fully recovered patients with a history of DSM-IV recur... Expand abstract
- Publication status:
- Peer review status:
- Peer reviewed
- Author's Original
- Copyright holder:
- Elsevier B. V.
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- Citation: Taylor, M. J. et al. (2009). 'Normal glutamate but elevated myo-inositol in anterior cingulate cortex in recovered depressed patients', Journal of Affective Disorders, 119(1-3), 186-189. [Available at http://www.sciencedirect.com/science/journal/01650327].
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