Fluoroquinolone resistance in Streptococcus pneumoniae in United States since 1994-1995.

Journal article

The in vitro activities of ciprofloxacin, levofloxacin, gatifloxacin, and moxifloxacin against a large collection of clinical isolates of Streptococcus pneumoniae (n = 4,650) obtained over a 5-year period, 1994-1995 through 1999-2000, were assessed as part of a longitudinal multicenter U.S. surveillance study of antimicrobial resistance. Three sampling periods were used during this investigation, the winter seasons of 1994-1995, 1997-1998, and 1999-2000; and 1,523, 1,596 and 1,531 isolates we...

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Authors: Brueggemann, A; Coffman, S; Rhomberg, P; Huynh, H; Almer, L

• Publication status: Published
• Journal: Antimicrobial agents and chemotherapy
• Volume: 46
• Issue: 3
• Pages: 680-688
• Publication date: 2002-03-01
• DOI: 10.1128/aac.46.3.680-688.2002
• EISSN: 1098-6596
• ISSN: 0066-4804
• Language: English
• Keywords: Microbial Sensitivity Tests; Reserpine; Anti-Infective Agents; Amino Acid Substitution; Streptococcus pneumoniae; DNA Topoisomerase IV; Pneumococcal Infections; Drug Resistance, Microbial; United States; Fluoroquinolones; DNA Gyrase; DNA, Bacterial; Humans; Reverse Transcriptase Polymerase Chain Reaction