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Journal article

Surfactant proteins SP-A and SP-D: structure, function and receptors.

Abstract:

Surfactant proteins, SP-A and SP-D, are collagen-containing C-type (calcium dependent) lectins called collectins, which contribute significantly to surfactant homeostasis and pulmonary immunity. These highly versatile innate immune molecules are involved in a range of immune functions including viral neutralization, clearance of bacteria, fungi and apoptotic and necrotic cells, down regulation of allergic reaction and resolution of inflammation. Their basic structures include a triple-helical...

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Publication status:
Published

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Authors


Kishore, U More by this author
Greenhough, TJ More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
Shrive, AK More by this author
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Journal:
Molecular immunology
Volume:
43
Issue:
9
Pages:
1293-1315
Publication date:
2006-03-05
DOI:
EISSN:
1872-9142
ISSN:
0161-5890
URN:
uuid:03bc70c2-d080-4360-9616-48b80f43d546
Source identifiers:
241783
Local pid:
pubs:241783

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