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Journal article

Influenza infection rates, measurement errors and the interpretation of paired serology.

Abstract:

Serological studies are the gold standard method to estimate influenza infection attack rates (ARs) in human populations. In a common protocol, blood samples are collected before and after the epidemic in a cohort of individuals; and a rise in haemagglutination-inhibition (HI) antibody titers during the epidemic is considered as a marker of infection. Because of inherent measurement errors, a 2-fold rise is usually considered as insufficient evidence for infection and seroconversion is theref...

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Publication status:
Published

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Publisher copy:
10.1371/journal.ppat.1003061

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Journal:
PLoS pathogens
Volume:
8
Issue:
12
Pages:
e1003061
Publication date:
2012-01-01
DOI:
EISSN:
1553-7374
ISSN:
1553-7366
URN:
uuid:03ba90dc-c84e-49e2-94e3-6f7ce6efda71
Source identifiers:
369855
Local pid:
pubs:369855

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