- Abstract:
-
Serological studies are the gold standard method to estimate influenza infection attack rates (ARs) in human populations. In a common protocol, blood samples are collected before and after the epidemic in a cohort of individuals; and a rise in haemagglutination-inhibition (HI) antibody titers during the epidemic is considered as a marker of infection. Because of inherent measurement errors, a 2-fold rise is usually considered as insufficient evidence for infection and seroconversion is theref...
Expand abstract - Publication status:
- Published
- Files:
-
-
(pdf, 852.6KB)
-
- Publisher copy:
- 10.1371/journal.ppat.1003061
-
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- Journal:
- PLoS pathogens
- Volume:
- 8
- Issue:
- 12
- Pages:
- e1003061
- Publication date:
- 2012-01-01
- DOI:
- EISSN:
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1553-7374
- ISSN:
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1553-7366
- URN:
-
uuid:03ba90dc-c84e-49e2-94e3-6f7ce6efda71
- Source identifiers:
-
369855
- Local pid:
- pubs:369855
- Copyright date:
- 2012
Journal article
Influenza infection rates, measurement errors and the interpretation of paired serology.
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