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Journal article

Tight control for Crohn's disease with adalimumab-based treatment is cost-effective: an economic assessment of the CALM trial

Abstract:

Objective To evaluate the cost-effectiveness of an inflammatory biomarker and clinical symptom directed tight control strategy (TC) compared with symptom-based clinical management (CM) in patients with Crohn’s disease (CD) naïve to immunosuppressants and biologics using a UK public payer perspective.

Design A regression model estimated weekly CD Activity Index (CDAI)-based transition matrices (remission: CDAI <150, moderate: CDAI ≥150 to <300,...

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Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1136/gutjnl-2019-318256

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Oxford college:
Linacre College
Role:
Author
More by this author
Role:
Author
ORCID:
0000-0003-4027-7365
Publisher:
BMJ Publishing Group Publisher's website
Journal:
Gut Journal website
Volume:
69
Issue:
4
Pages:
658-664
Publication date:
2019-07-08
Acceptance date:
2019-06-12
DOI:
EISSN:
1468-3288
ISSN:
0017-5749
Pmid:
31285357
Language:
English
Keywords:
Pubs id:
pubs:1033058
UUID:
uuid:03ab2042-b70f-4e25-8240-bfc35e965c52
Local pid:
pubs:1033058
Source identifiers:
1033058
Deposit date:
2019-07-20

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