- Abstract:
-
To optimize vaccination strategies, it is important to use protocols that can 'jump-start' immune responses by harnessing cells of the innate immune system to assist the expansion of antigen-specific B and T cells. In this Review, we discuss the evidence indicating that invariant natural killer T (iNKT) cells can positively modulate dendritic cells and B cells, and that their pharmacological activation in the presence of antigenic proteins can enhance antigen-specific B- and T-cell responses....
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1038/nri2451
-
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- Journal:
- Nature reviews. Immunology
- Volume:
- 9
- Issue:
- 1
- Pages:
- 28-38
- Publication date:
- 2009-01-05
- DOI:
- EISSN:
-
1474-1741
- ISSN:
-
1474-1733
- URN:
-
uuid:03a64a51-1068-48c3-84d0-fb7985f2ca22
- Source identifiers:
-
21202
- Local pid:
- pubs:21202
- Language:
- English
- Keywords:
- Copyright date:
- 2009
Journal article
Harnessing invariant NKT cells in vaccination strategies.
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