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Hyperpolarized noble gas magnetic resonance imaging of the animal lung: Approaches and applications

Abstract:

Hyperpolarized noble gas (HNG) magnetic resonance (MR) imaging is a very promising noninvasive tool for the investigation of animal models of lung disease, particularly to follow longitudinal changes in lung function and anatomy without the accumulated radiation dose associated with x rays. The two most common noble gases for this purpose are 3He (helium 3) and 129Xe (xenon 129), the latter providing a cost-effective approach for clinical applications. Hyperpolarization is typically achieved ...

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Publication status:
Published

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Publisher copy:
10.1063/1.3112143

Authors


Santyr, GE More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
Parra-Robles, JM More by this author
Ouriadov, AV More by this author
Journal:
JOURNAL OF APPLIED PHYSICS
Volume:
105
Issue:
10
Pages:
102004-102004
Publication date:
2009-05-15
DOI:
ISSN:
0021-8979
URN:
uuid:0388c6c8-25d1-442e-ba15-d199477dcd45
Source identifiers:
441918
Local pid:
pubs:441918

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