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A variant within the FTO confers susceptibility to diabetic nephropathy in Japanese patients with type 2 diabetes

Abstract:

To explore novel genetic loci for diabetic nephropathy, we performed genome-wide association studies (GWAS) for diabetic nephropathy in Japanese patients with type 2 diabetes. We analyzed the association of 5,768,242 single nucleotide polymorphisms (SNPs) in Japanese patients with type 2 diabetes, 2,380 nephropathy cases and 5,234 controls. We further performed GWAS for diabetic nephropathy using independent Japanese patients with type 2 diabetes, 429 cases and 358 controls and the results of...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's Version

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Publisher copy:
10.1371/journal.pone.0208654

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Publisher:
Public Library of Science Publisher's website
Journal:
PloS one Journal website
Volume:
13
Issue:
12
Pages:
e0208654
Publication date:
2018-12-19
Acceptance date:
2018-11-20
DOI:
EISSN:
1932-6203
Pubs id:
pubs:954640
URN:
uri:037f07a5-6e50-44aa-8f25-54fcaa99854e
UUID:
uuid:037f07a5-6e50-44aa-8f25-54fcaa99854e
Local pid:
pubs:954640
Language:
English

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