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Fifty years on: serotonin and depression

Abstract:
It has been over 50 years since the original serotonin hypothesis was proposed by the British Psychiatrist Alec Coppen. Recently, some authors have questioned the validity of the hypothesis. In this narrative review, we summarise the evidence for the serotonin hypothesis of depression, focusing on psychopharmacology and molecular imaging, as well as systems-level neuroscience.
Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1177/02698811231161813

Authors

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Institution:
University of Oxford
Division:
MSD
Department:
Psychiatry
Oxford college:
St Cross College
Role:
Author
ORCID:
0000-0001-9108-3144


Publisher:
SAGE Publications
Journal:
Journal of Psychopharmacology More from this journal
Publication date:
2023-03-20
Acceptance date:
2023-03-02
DOI:
EISSN:
1461-7285
ISSN:
0269-8811


Language:
English
Keywords:
Pubs id:
1333992
Local pid:
pubs:1333992
Deposit date:
2023-03-23
ARK identifier:

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