The genesis and source of the H7N9 influenza viruses causing human infections in China.

Journal article

A novel H7N9 influenza A virus first detected in March 2013 has since caused more than 130 human infections in China, resulting in 40 deaths. Preliminary analyses suggest that the virus is a reassortant of H7, N9 and H9N2 avian influenza viruses, and carries some amino acids associated with mammalian receptor binding, raising concerns of a new pandemic. However, neither the source populations of the H7N9 outbreak lineage nor the conditions for its genesis are fully known. Using a combination ...

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Authors: Lam, T; Wang, J; Shen, Y; Zhou, B; Duan, L

• Publication status: Published
• Journal: Nature
• Volume: 502
• Issue: 7470
• Pages: 241-244
• Publication date: 2013-10-01
• DOI: 10.1038/nature12515
• EISSN: 1476-4687
• ISSN: 0028-0836
• Language: English
• Keywords: Genes, Viral; Animals; Chickens; Influenza in Birds; Ducks; Humans; Phylogeny; Reassortant Viruses; China; Influenza, Human; Influenza A virus; Molecular Sequence Data; Influenza A Virus, H9N2 Subtype; Influenza A Virus, H7N7 Subtype