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The relationship between secreted and cell surface antigen-binding molecules synthesized by T cells. I. Function-related isotypic determinants on T cells defined by antisera to antigen-specific helper and suppressor factors.

Abstract:

Rabbit antisera have been used to define 'constant region' markers which distinguish between mouse T cell-derived helper and suppressor factors, regardless of their antigen-specificity or strain of origin. These antisera have also been shown to bind to functional T-cell lines. After several absorption steps, rabbit anti-helper factor serum bound specifically to mouse helper cell lines, whereas rabbit anti-suppressor factor serum bound specifically to suppressor cell lines. Neither antiserum b...

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Authors


Culbert, EJ More by this author
Kontiainen, S More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Journal:
Immunology
Volume:
53
Issue:
3
Pages:
481-490
Publication date:
1984-11-05
EISSN:
1365-2567
ISSN:
0019-2805
URN:
uuid:036b4c4a-ce0b-4110-8d0f-89ef8f9a8e72
Source identifiers:
481824
Local pid:
pubs:481824

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