Journal article icon

Journal article

Membrane trafficking of CD98 and its ligand galectin 3 in BeWo cells--implication for placental cell fusion.

Abstract:

CD98 heavy chain (CD98hc), expressed at high levels in developing human trophoblasts, is an integral membrane protein with multiple N-linked glycosylation sites and known to be important for cell fusion, adhesion, and amino acid transport. Western blotting and flow cytometry were used to study the effect of brefeldin A, an inhibitor of protein translocation through the Golgi, on CD98hc in the human placental trophoblast cell line BeWo. Although brefeldin A treatment caused increased cell surf...

Expand abstract
Publication status:
Published

Actions


Access Document


Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Redman, CW More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Obstetrics and Gynaecology
Journal:
The FEBS journal
Volume:
274
Issue:
11
Pages:
2715-2727
Publication date:
2007-06-05
DOI:
EISSN:
1742-4658
ISSN:
1742-464X
URN:
uuid:0362b701-ac71-4970-b132-1ede3591ad4e
Source identifiers:
113572
Local pid:
pubs:113572

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP