Journal article
Importance of the COMT gene for sex differences in brain function and predisposition to psychiatric disorders.
- Abstract:
-
As outlined elsewhere in this volume, sex differences can affect brain function and its dysfunction in psychiatric disorders. It is known that genetic factors contribute to these sex dimorphisms, but the individual genes have rarely been identified. The catechol-O-methyltransferase (COMT) gene, which encodes an enzyme that metabolises catechol compounds, including dopamine, is a leading candidate in this regard. COMT's enzyme activity, and the neurochemistry and behaviour of COMT knockout mic...
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Bibliographic Details
- Journal:
- Current topics in behavioral neurosciences
- Volume:
- 8
- Issue:
- 8
- Pages:
- 119-140
- Publication date:
- 2011-01-01
- DOI:
- EISSN:
-
1866-3389
- ISSN:
-
1866-3370
- Source identifiers:
-
166466
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:166466
- UUID:
-
uuid:034e9df0-10a6-4988-9787-29cd4fe698b5
- Local pid:
- pubs:166466
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2011
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