Journal article icon

Journal article

The effect of opioid receptor blockade on the neural processing of thermal stimuli.

Abstract:

The endogenous opioid system represents one of the principal systems in the modulation of pain. This has been demonstrated in studies of placebo analgesia and stress-induced analgesia, where anti-nociceptive activity triggered by pain itself or by cognitive states is blocked by opioid antagonists. The aim of this study was to characterize the effect of opioid receptor blockade on the physiological processing of painful thermal stimulation in the absence of cognitive manipulation. We therefore...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.1371/journal.pone.0012344

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
Expand authors...
Volkswagenstiftung More from this funder
Publisher:
Public Library of Science Publisher's website
Journal:
PloS one Journal website
Volume:
5
Issue:
8
Article number:
e12344
Publication date:
2010-01-01
DOI:
EISSN:
1932-6203
Source identifiers:
241730
Language:
English
Keywords:
UUID:
uuid:034c6368-cbe7-48ac-918f-ed78d40c3ac6
Local pid:
pubs:241730
Deposit date:
2012-12-19

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP