Journal article
Pacing a small cage: mutation and RNA viruses.
- Abstract:
-
RNA viruses have an extremely high mutation rate, and we argue that the most plausible explanation for this is a trade-off with replication speed. We suggest that research into further increasing this mutation rate artificially as an antiviral treatment requires a theoretical reevaluation, especially relating to the so-called error threshold. The main evolutionary consequence of a high mutation rate appears to have been to restrict RNA viruses to a small genome; they thus rapidly exploit a li...
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- Publication status:
- Published
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- Publisher copy:
- 10.1016/j.tree.2007.11.010
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Authors
Bibliographic Details
- Journal:
- Trends in ecology and evolution
- Volume:
- 23
- Issue:
- 4
- Pages:
- 188-193
- Publication date:
- 2008-04-01
- DOI:
- EISSN:
-
1872-8383
- ISSN:
-
0169-5347
- Source identifiers:
-
209267
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:209267
- UUID:
-
uuid:0326afa3-ed2e-4537-95e2-d8161abdcff8
- Local pid:
- pubs:209267
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2008
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